Endocrine Abstracts

The human genome is over 2 meters in length, which has to be folded in micrometer-sized nuclear space for proper functions. Although most of our understandings in the human genome are based on linear explanations, it has been speculated that the three-dimensional (3D) and high-order organization of the genome must play important roles in framing the mechanisms of nuclear process such as transcription regulation. Recent advance in 3D genome mapping technologies and sophisticate...